16 Feb 2026 09:00am to 05:00pm
Implementing the Estimand Framework in Clinical Trials
Workshop
Event Location
The University of Melbourne, “The Spot” building (Room 1022), 198 Berkeley St, Carlton
Speakers
Sabine is a statistician at the University of Melbourne and Doherty Institute. She completed her postgraduate training at the University of Hasselt (Belgium). Her experience lies mainly in the design,...
Anneke is a biostatistician at the Murdoch Childrens Research Institute and the University of Melbourne. She works in the Melbourne Children’s Trials Centre at the Royal Children's Hospital and at...
At the end of this course you will be familiar with the estimand framework for clinical trials. You will understand the elements of the estimand, including intercurrent events and the five suggested strategies for handling intercurrent events. You will understand how to analyse trials using some of these strategies.
Specific Learning Objectives and outcomes:
- Be familiar with the terminology of the estimand framework as detailed in the 2020 ICH E9 R1
- Understand what intercurrent events are
- Recognise the 5 strategies that have been suggested for handling intercurrent events as outlined in ICH E9(R1) (treatment policy, hypothetical, composite, while-on-treatment, and principal stratum) and understand their appropriateness in different trial scenarios
- Be able to translate research questions into well-defined estimands and integrate them into the trial protocol and statistical analysis plan
- Know how to apply appropriate statistical methods that correspond to the chosen/defined estimand
- Critically appraise trial examples for consistency between research questions, estimand and analysis
Target audience: This workshop is aimed at trialists with or without a statistical background, however the workshop will include examples of analyses which will be more suitable for attendees with experience in the analysis of clinical trials.
Date: Monday 16th February
Registration prices: Standard $540, Student $390
Registration is now open via Trybooking