Research Projects

Research Projects

Causal inference in health data science: advancing understanding and methods

Dr Margarita Moreno-Betancur

The ultimate goal of medical and health research is to improve patient outcomes and population health. As a result, the overwhelming majority of clinical and public health research studies ask “causal” questions, concerning the effect of treatments, policies, behaviours and other exposures on health outcomes. In many cases, especially in the current era of data deluge, these studies rely on observational (non-randomised) data to address causal questions. As a result, recent understanding of the challenges of making causal inferences, and related analytical methods, are critical to modern health data science.

This program of research aims to develop, disseminate and promote the adoption of modern causal thinking and related methods in medical and health research, through research within the following strands (sometimes overlapping):

  • Practice of causal inference, especially in longitudinal life-course epidemiological studies
  • Mediation analysis methods
  • Data-adaptive methods for causal inference
  • Missing data in causal inference (see also here)

Collaborators:
Prof John Carlin 
Prof Stijn Vansteelandt

Enhancing aspects of time-to-event analysis methodology in randomised trials

Prof. Rory Wolfe
In time-to-event ("survival") analysis the direct modelling of the time until an event occurs, through accelerated failure time models, is an important and underutilised approach.

Current ViCBiostat post doc and student research

In April 2018, the ViCBiostat team met for a brief review of recent research and work in progress. The presentations from students and post docs, available here, provide an overview of a range of our current research.